Induced pluripotent stem cells in spermatogenesis: Progress in current studies / 中华男科学杂志
National Journal of Andrology
;
(12): 925-930, 2015.
Artigo
em Chinês
| WPRIM
| ID: wpr-275993
ABSTRACT
Spermatogenesis is a complex process. Current knowledge about human spermatogenesis is mainly based on the mouse model while little is known about the initial stage of this fundamental process in humans. The establishment of the model of spermatogenesis in vitro may contribute to an overall understanding of male germ cell development, an insight into the mechanisms of infertility, and clinical management of male infertility. This review summarizes current knowledge about the generation of germ cell-like cells from induced pluripotent stem cells (iPSCs) in vitro and discusses the potential application of iPSCs in the treatment of male infertility.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Espermatogênese
/
Terapêutica
/
Diferenciação Celular
/
Células-Tronco Pluripotentes Induzidas
/
Células Germinativas
/
Infertilidade Masculina
Limite:
Animais
/
Humanos
/
Masculino
Idioma:
Chinês
Revista:
National Journal of Andrology
Ano de publicação:
2015
Tipo de documento:
Artigo
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