Morinda Officinalis How improves cellphone radiation-induced abnormality of LH and LHR in male rats / 中华男科学杂志

ABSTRACT

<p><b>OBJECTIVE</b>To investigate the effects of Morina Officinalis How (MOH) on the abnormal levels of serum luteotrophic hormone (LH) and LH receptor (LHR) in the testis tissue induced by cellphone radiation (CPR) in rats.</p><p><b>METHODS</b>Fifty adult male SD rats were randomly divided into five groups of equal number sham CPR, untreated CPR, negative double distilled water (DDW) control, aqueous MOH extract, and alcohol MOH extract. All the animals were exposed to mobile phone radiation except those of the sham CPR group. Then, the rats of the latter two groups were treated intragastrically with MOH at 20 g per kg of the body weight per day in water and alcohol, respectively. After 2. weeks of treatment, all the rats were sacrificed for measurement of the levels of serum LH and LHR in the testis tissue.</p><p><b>RESULTS</b>The levels of serum LH and LHR were 30.15 ± 8.71 and 33.28 ± 6.61 in the aqueous MOH group and 0.96 ± 0.06 and 0.94 ± 0.08 in the alcohol MOH group, both significantly decreased as compared with the negative DDW controls (P < 0.05), but with no remarkable difference between the two MOH groups (P > 0.05).</p><p><b>CONCLUSION</b>MOH can improve CPR-induced abnormality of LH and LHR in adult male rats.</p>