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Relationship between anogenital distance and cryptorchidism in human newborns / 中华男科学杂志
National Journal of Andrology ; (12): 432-435, 2015.
Artigo em Chinês | WPRIM | ID: wpr-276079
ABSTRACT
<p><b>OBJECTIVE</b>To explore the relation of the anogenital distance (AGD) with cryptorchidism in male newborns.</p><p><b>METHODS</b>This study included 350 male infants delivered in two community hospitals between September 2013 and September 2014. Within 24 hours after birth, a pediatric surgeon measured the AGD of the neonates and determined whether they had cryptorchidism. According to the testicular position, we divided the undescended testes into three types upper scrotal, inguinal, and non-palpable.</p><p><b>RESULTS</b>Totally 39 cases of cryptorchidism were found in the 350 newborns. The AGD of the cryptorchidism infants was significantly shorter than that of the normal neonates ([2.01 ± 0.22] vs [2.35 ± 0.19] cm, P < 0.01), and statistically significant differences remained even when preterm and low birth-weight infants were excluded ([2.32 ± 0.14] vs [2.06 ± 0.19] cm; (2.37 ± 0.17) cm vs (2.12 ± 0.12) cm, all P < 0.01). The newborns with higher-position cryptorchidism had a shorter AGD, though with no significant difference (F = 0.434, P > 0.05). No significant differences were observed in the AGD between unilateral and bilateral cryptorchidism ([1.96 ± 0.13] vs [2.02 ± 0.17] cm, P > 0.05).</p><p><b>CONCLUSION</b>Shorter AGD is associated with a higher incidence of cryptorchidism in male newborns. AGD could serve as a potential biomarker for disruption of androgen action during the male programming window period.</p>
Assuntos
Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Períneo / Fisiologia / Anormalidades Congênitas / Recém-Nascido de Baixo Peso / Recém-Nascido Prematuro / Criptorquidismo / Diagnóstico / Androgênios Tipo de estudo: Estudo diagnóstico Limite: Humanos / Masculino / Recém-Nascido Idioma: Chinês Revista: National Journal of Andrology Ano de publicação: 2015 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Períneo / Fisiologia / Anormalidades Congênitas / Recém-Nascido de Baixo Peso / Recém-Nascido Prematuro / Criptorquidismo / Diagnóstico / Androgênios Tipo de estudo: Estudo diagnóstico Limite: Humanos / Masculino / Recém-Nascido Idioma: Chinês Revista: National Journal of Andrology Ano de publicação: 2015 Tipo de documento: Artigo