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Interventional therapy combining Seed of Job's-stears with lipiodol for hepatoma-bearing rats / 中华肝脏病杂志
Chinese Journal of Hepatology ; (12): 452-454, 2002.
Artigo em Chinês | WPRIM | ID: wpr-276536
ABSTRACT
<p><b>OBJECTIVE</b>To study the effect of the interventional therapy of hepatoma-bearing rat by Seed of Job's-stears (SJS) injection combining with lipiodol.</p><p><b>METHODS</b>To evaluate the effect of SJS as a medicament which can be used in interventional therapy, we repeated the hepatoma-bearing rats, and treated them by interventional therapy with SJS referring to the method which Lindel set up, comparing its effect to which of chemical medicines and lipiodol.</p><p><b>RESULTS</b>SJS or lipiodol alone had an inhibiting effect to liver cancer. The tumor growth rates were 13.89%, 14.05%, and the tumor inhibiting rates reached 38.10%, 37.49%. The curative effect of the SJS/lipiodol group was the best, and its growth rate and inhibiting rate were 3.36% and 85.03%, respectively better than the SJS group and lipiodol group (P<0.01). There was no statistically significant difference between the effect of the SJS/lipiodol group and the mitomycin/lipiodol group. The survival period of SJS/lipiodol group was longer than the rest groups (P<0.01 or P<0.05).</p><p><b>CONCLUSIONS</b>The interventional therapy by SJS/lipiodol has obvious inhibitory effect on the growth of hepatoma-bearing rats, which is similar to that of MMC/lipiodol. This inhibiting effect is better than that of the SJS or lipiodol group. SJS/lipiodol can prolong the survival period of hepatoma-bearing rats obviously, and this effect is better than that of single lipiodol, SJS or MMC/lipiodol.</p>
Assuntos
Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Patologia / Sementes / Extratos Vegetais / Análise de Sobrevida / Divisão Celular / Química / Mitomicina / Ratos Wistar / Óleo Iodado / Coix Limite: Animais Idioma: Chinês Revista: Chinese Journal of Hepatology Ano de publicação: 2002 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Patologia / Sementes / Extratos Vegetais / Análise de Sobrevida / Divisão Celular / Química / Mitomicina / Ratos Wistar / Óleo Iodado / Coix Limite: Animais Idioma: Chinês Revista: Chinese Journal of Hepatology Ano de publicação: 2002 Tipo de documento: Artigo