The significance of maternal serum and umbilical cord blood leptin concentration with intrauterine fetal growth restriction and/or preeclampsia / 대한산부인과학회지
Korean Journal of Obstetrics and Gynecology
;
: 1336-1343, 2007.
Artigo
em Coreano
| WPRIM
| ID: wpr-27676
ABSTRACT
OBJECTIVE:
To ascertain whether fetal growth restriction with or without preeclampsia is associated with alteration of leptin concentration in maternal and umbilical cord serum.METHODS:
Maternal serum and umbilical cord blood leptin concentrations were determined by ELISA assay in 25 women with singletone pregnancies complicated by fetal growth restriction without preeclampsia (IUGR), in 11 women with singletone pregnancies complicated by fetal growth restriction with preeclampsia (IUGR+PE), in 9 women with singletone pregnancies complicated by preeclampsia without fetal growth restriction (PE), and in 13 women with uncomplicated singletone pregnancies (Control).RESULTS:
Maternal weight and BMI before pregnancy and in delivery were significantly different among groups. The lowest weight and BMI before pregnancy and in delivery was group IUGR. Neonatal birth weight was significantly different among groups. The lowest birth weight was group IUGR+PE. Maternal serum leptin concentration and umbilical cord leptin concentration were not significantly different among groups. Maternal serum leptin levels were not significantly correlated with maternal BMI or with neonatal birth weight. Umbilical cord blood leptin levels were significantly correlated with neonatal birth weight.CONCLUSION:
Maternal serum leptin concentration and umbilical cord blood leptin levels were independent of presence of preeclampsia and/or IUGR. Umbilical cord blood leptin reflects neonatal birth weight.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Pré-Eclâmpsia
/
Cordão Umbilical
/
Peso ao Nascer
/
Ensaio de Imunoadsorção Enzimática
/
Leptina
/
Desenvolvimento Fetal
/
Sangue Fetal
/
Retardo do Crescimento Fetal
Limite:
Feminino
/
Humanos
/
Gravidez
Idioma:
Coreano
Revista:
Korean Journal of Obstetrics and Gynecology
Ano de publicação:
2007
Tipo de documento:
Artigo
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