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Screening analysis of irregular antibodies from random donor population in Shaoguan area / 中国实验血液学杂志
Journal of Experimental Hematology ; (6): 630-631, 2007.
Artigo em Chinês | WPRIM | ID: wpr-276857
ABSTRACT
The study was purposed to analyze the frequency and distribution of irregular antibodies in Shaoguan area. Screening 15 033 random donor antibodies in Shaoguan area by screening cells, polybrene and antiglobulin tests. The results indicated that the irregular antibodies were found in 42 samples. The frequency of irregular antibodies in female was higher than that in male (P < 0.001), and Rh blood group antibodies such as anti-D, anti-E, and anti-Ec C were common (47.6%). 2 samples of Le antibodies were failed to be found by polybrene test. 2 samples of irregular antibodies with titer 2 were undiscovered by screening test of 10 pooled samples. In conclusion, because of irregular antibodies resulting in hemolytic transfusion reaction, the investigation of frequency and distribution of irregular antibodies is very important for safe transfusion. Antibody screening must be done for female donors, and especially for massive plasma transfusion of patients with severe and dangerous illness and infants so as to ensure safety.
Assuntos
Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Sistema do Grupo Sanguíneo Rh-Hr / Sangue / Doadores de Sangue / China / Programas de Rastreamento / Imunoglobulina rho(D) / Alergia e Imunologia / Eritrócitos / Isoanticorpos Tipo de estudo: Ensaio Clínico Controlado / Estudo diagnóstico / Estudo prognóstico / Estudo de rastreamento Limite: Adolescente / Adulto / Feminino / Humanos / Masculino País/Região como assunto: Ásia Idioma: Chinês Revista: Journal of Experimental Hematology Ano de publicação: 2007 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Sistema do Grupo Sanguíneo Rh-Hr / Sangue / Doadores de Sangue / China / Programas de Rastreamento / Imunoglobulina rho(D) / Alergia e Imunologia / Eritrócitos / Isoanticorpos Tipo de estudo: Ensaio Clínico Controlado / Estudo diagnóstico / Estudo prognóstico / Estudo de rastreamento Limite: Adolescente / Adulto / Feminino / Humanos / Masculino País/Região como assunto: Ásia Idioma: Chinês Revista: Journal of Experimental Hematology Ano de publicação: 2007 Tipo de documento: Artigo