A clinical analysis of glucagonoma syndrome (four cases reported) / 中国医学科学院学报
Acta Academiae Medicinae Sinicae
; (6): 210-213, 2003.
Article
em Zh
| WPRIM
| ID: wpr-278093
Biblioteca responsável:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To study the clinical features, diagnosis, and treatment of glucagonoma syndrome (GS) for providing clues for the recognition of this disorder in clinical practice.</p><p><b>METHOD</b>The clinical and laboratory findings of four confirmed patients with GS were analyzed retrospectively.</p><p><b>RESULTS</b>All four patients had typical clinical manifestations of necrolytic migratory erythema (NME), elevated glucagon level in serum and hepatic metastasis. The skin rashes disappeared gradually and serum glucagon level decreased after operation and somatostatin treatment.</p><p><b>CONCLUSIONS</b>NME is the most specific clinical finding of GS. Biopsy of the lesions, glucagon level in serum and various radiological examinations should be done in order to confirm the diagnosis. Surgical resection, chemotherapy, and somatostatin are the main therapies of GS.</p>
Texto completo:
1
Índice:
WPRIM
Assunto principal:
Neoplasias Pancreáticas
/
Terapêutica
/
Somatostatina
/
Estudos Retrospectivos
/
Usos Terapêuticos
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Diagnóstico
/
Glucagonoma
Tipo de estudo:
Diagnostic_studies
/
Observational_studies
Limite:
Adult
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Female
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Humans
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Male
Idioma:
Zh
Revista:
Acta Academiae Medicinae Sinicae
Ano de publicação:
2003
Tipo de documento:
Article