Genetic polymorphism of 9 STR loci in Han nation population in Shandong Province / 中国医学科学院学报
Acta Academiae Medicinae Sinicae
;
(6): 620-625, 2002.
Artigo
em Chinês
| WPRIM
| ID: wpr-278125
ABSTRACT
<p><b>OBJECTIVE</b>To study genetic polymorphism of 9 STR loci in Han nation population in Shangdong Province.</p><p><b>METHODS</b>We investigated 100 unrelated individuals of Han nation population in Shandong Province and studied their genetic distribution of 9 STR loci and Amelogenin locus. Primers of 10 loci were labeled with the NHS-ester fluorescent dye 5-FAM (blue), Joe (green) or NED (yellow). The data of Han nation population were generated by multiple amplification and subjected to GeneScan, genotype and genetic distribution analysis.</p><p><b>RESULTS</b>83 alleles and 220 genotypes were observed, with the corresponding frequency of 0.0050-0.4050 and 0.0100-0.2100. The average of heterozygosity was 0.7778, the accumulated discrimination power was 0.9999. The accumulated probability of exclusion paternity was 0.9999. The polymorphism information content was 0.5823-0.8396.</p><p><b>CONCLUSIONS</b>Chi-Square test indicated that the distribution of genotypes agreed with Hardy-Weinberg equilibrium.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Polimorfismo Genético
/
Sequências Repetitivas de Ácido Nucleico
/
Marcadores Genéticos
/
China
/
Sequências de Repetição em Tandem
/
Alelos
/
Etnologia
/
Frequência do Gene
/
Genética
/
Genótipo
Limite:
Humanos
País/Região como assunto:
Ásia
Idioma:
Chinês
Revista:
Acta Academiae Medicinae Sinicae
Ano de publicação:
2002
Tipo de documento:
Artigo
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