Genotyping of HLA-DRB1 by PCR-SSP in Yunnan Lahu ethnic groups / 中国医学科学院学报
Acta Academiae Medicinae Sinicae
;
(6): 389-392, 2002.
Artigo
em Chinês
| WPRIM
| ID: wpr-278157
ABSTRACT
<p><b>OBJECTIVE</b>To investigate polymorphism of HLA-DRB1 in Chinese Lahu population in Yunnan.</p><p><b>METHODS</b>Polymerase chain reaction-sequence specific primers (PCR-SSP) were used to determine HLA-DRB1 genotypes of 110 unrelated healthy Lahu minority people of Yunnan Province.</p><p><b>RESULTS</b>Sixteen alleles of DRB1 were detected in this study. The results of test showed that the genotype distributions observed were corresponded with the Hardy-Weinberg equilibrium.</p><p><b>CONCLUSION</b>This study has obtained a more comprehensive and accurate data set of the normal allele frequencies of HLA-DRB1 in Chinese Lahu population in Yunnan Province, which may be of significance in the studies on population genetics and disease association.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Etnicidade
/
Antígenos HLA-DR
/
Reação em Cadeia da Polimerase
/
Primers do DNA
/
Povo Asiático
/
Cadeias HLA-DRB1
/
Frequência do Gene
/
Genética
/
Genótipo
/
Métodos
Limite:
Feminino
/
Humanos
/
Masculino
Idioma:
Chinês
Revista:
Acta Academiae Medicinae Sinicae
Ano de publicação:
2002
Tipo de documento:
Artigo
Similares
MEDLINE
...
LILACS
LIS