Comparative study of pulmonary function after conventional ultrafiltration or modified ultrafiltration during cardiac surgery of infants / 中国医学科学院学报

ABSTRACT

<p><b>OBJECTIVE</b>To compare the effects of conventional ultrafiltration and modified ultrafiltration in protecting patients' pulmonary function during cardiopulmonary bypass.</p><p><b>METHODS</b>Thirty infants patients (less than 7 kg) were divided into two groups: conventional ultrafiltration group (CUF, n = 15) and modified ultrafiltration group (MUF, n = 15). The volume of ultrafiltration, transfusion, hematocrit (HCT) before and after ultrafiltration, patients' respiration function (respiration index, A-aDO2, airway pressure), the time of mechanical ventilation and ICU in the two groups were respectively monitored.</p><p><b>RESULTS</b>The transfusion in MUF group was significantly less than in CUF group (P < 0.01), and the volume of ultrafiltration in MUF group was significantly more than in CUF group (P < 0.01). The time of mechanical ventilation and ICU staying in MUF group were significantly shorter in MUF group than that in CUF group (P < 0.05). At 12 and 24 hours after operations, the A-aDO2 in MUF group was lower than that in CUF group (P < 0.05), and the respiratory index in MUF group was higher than that in CUF group (P < 0.05).</p><p><b>CONCLUSION</b>The modified ultrafiltration can effectively improve pulmonary function after operations for low weight infants.</p>