Isolation and characterization of xanthine oxidase inhibitory constituents of Pyrenacantha staudtii / 药学学报
Acta Pharmaceutica Sinica
;
(12): 390-394, 2009.
Artigo
em Inglês
| WPRIM
| ID: wpr-278251
ABSTRACT
Six compounds have been isolated from the leaves of Pyrenacantha staudtii, two of which are new compounds. The new compounds have been characterized as kaempherol 3-O-beta-rhamnopyranosyl (1-->6)-beta-D-glucopyranoside (1) and 4-beta-glucopyranosyl-(2-furyl)-5-methy-1,2-glucopyranoside phenylmethanone (2). The known compounds are 3-pyridinecarboxylic acid (3), beta-sitosterol (4), sitosterol 3-O-beta-glucopyranoside (5) and taraxerol (6). Their structures were determined by spectroscopic and chemical evidences. The two new compounds together with 3-pyridinecarboxylic acid showed significant in vitro xanthine oxidase inhibitory activity. To the best of our knowledge, this is the first report of these compounds from this plant.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Farmacologia
/
Plantas Medicinais
/
Xantina Oxidase
/
Estrutura Molecular
/
Química
/
Folhas de Planta
/
Magnoliopsida
/
Quempferóis
/
Inibidores Enzimáticos
/
Glucosídeos
Idioma:
Inglês
Revista:
Acta Pharmaceutica Sinica
Ano de publicação:
2009
Tipo de documento:
Artigo
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