Clinical and laboratory features of acute monocytic leukemia with B lymphoproliferative disorders / 中华血液学杂志
Chinese Journal of Hematology
;
(12): 710-714, 2012.
Artigo
em Chinês
| WPRIM
| ID: wpr-278328
ABSTRACT
<p><b>OBJECTIVE</b>To identify the clinical and pathological features of acute myeloid leukemia with B lymphoproliferative disorders.</p><p><b>METHODS</b>The characteristics of 3 cases of acute monocytic leukemia with untreated chronic lymphocytic leukemia/monoclonal B-cell lymphocytosis were reported with literatures review.</p><p><b>RESULTS</b>The patients presented with a history of anemia, bleeding and/or fever. Acute monocytic leukemia was diagnosed by bone marrow morphology, cytochemistry and pathology studies. Immunophenotyping by flow cytometry analysis showed a significant population of absolute B-lymphocyte count of > 5×10(9)/L in a patients, similar to that of chronic lymphocytic leukemia.</p><p><b>CONCLUSIONS</b>The association of acute monocytic leukemia and untreated chronic lymphocytic leukemia/monoclonal B-cell lymphocytosis was a rare event. The abnormal B lymphocytes was likely to be misdiagnosis. Thus, it was important to combine several kinds of laboratory studies, especially flow cytometry to identify this rare disorder.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Patologia
/
Linfócitos B
/
Leucemia Monocítica Aguda
/
Diagnóstico
/
Linfocitose
Tipo de estudo:
Estudo diagnóstico
/
Estudo prognóstico
Limite:
Idoso
/
Feminino
/
Humanos
Idioma:
Chinês
Revista:
Chinese Journal of Hematology
Ano de publicação:
2012
Tipo de documento:
Artigo
Similares
MEDLINE
...
LILACS
LIS