Advancements in diagnosis and management of paroxysmal nocturnal hemoglobinuria - review / 中国实验血液学杂志
Journal of Experimental Hematology
;
(6): 1267-1271, 2012.
Artigo
em Chinês
| WPRIM
| ID: wpr-278392
ABSTRACT
Paroxysmal nocturnal hemoglobinuria (PNH) is a hemolytic disease of abnormally activated complement. FLAER diagnosis is a higher sensitive and specific method, which makes PNH patients to be early discovered and treated. Non-typical symptoms including thrombosis, pulmonary hypertension and chronic kidney disease in PNH have been caused increasing attention. Eculizumab monoclonal antibody has greatly improved the current treatment status of PNH. PNH can be cured thoroughly by allogeneic hematopoietic stem cell transplantation. In this article, the FLAER diagnosis, clinic symptoms and progress of treatment in patients with PNH are reviewed.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Terapêutica
/
Transplante de Células-Tronco Hematopoéticas
/
Usos Terapêuticos
/
Diagnóstico
/
Anticorpos Monoclonais Humanizados
/
Hemoglobinúria Paroxística
Tipo de estudo:
Estudo diagnóstico
Limite:
Humanos
Idioma:
Chinês
Revista:
Journal of Experimental Hematology
Ano de publicação:
2012
Tipo de documento:
Artigo
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