Major role of stromal cell derived factor and its receptor CXCR4 in the mobilization and homing of hematopoietic stem/progenitor cells - review / 中国实验血液学杂志
Journal of Experimental Hematology
;
(6): 115-119, 2004.
Artigo
em Chinês
| WPRIM
| ID: wpr-278786
ABSTRACT
Stromal cell derived factor (SDF), expressing on bone marrow stromal cells is a CXC-type chemokine, which specifically chemoattracts hematopoietic stem cells (HSCs) expressing CXCR4. SDF plays important roles in homing and mobilizing of HSCs. In this paper the regulatory mechanism of SDF/CXCR4 in the HSC migration process is mainly reviewed.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Fisiologia
/
Transdução de Sinais
/
Receptores CXCR4
/
Quimiocinas CXC
/
Mobilização de Células-Tronco Hematopoéticas
/
Quimiocina CXCL12
Limite:
Humanos
Idioma:
Chinês
Revista:
Journal of Experimental Hematology
Ano de publicação:
2004
Tipo de documento:
Artigo
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