A case of reversible posterior leukoencephalopathy syndrome (RPLS) with eclampsia / 대한산부인과학회지

ABSTRACT

The reversible posterior leukoencephalopathy syndrome (RPLS) was first described by Hinchey et al. It is characterized by reversible posterior predominant white and gray matter lesions on brain magnetic resonance imaging (MRI) in patients with renal insufficiency or hypertension, or immunosuppression. The findings on neuroimaging are characteristic of subcortical edema without infarction. Patients with RPLS show various kinds of neurologic abnormalities characterized by headache, nausea, vomiting, visual disturbances, altered mental status, decreased alertness, seizures, and focal neurologic signs. The clinical and radiological findings usually resolve within two to three weeks when the underlying cause is removed. In this report we describe the case of RPLS with eclampsia in a 24-year-old woman, which appears to be involved in areas of the occipital, frontal, and parietal lobes. A brief review of the literature is also presented.