Effects of jiantai liquid on the expression of estrogen/progesterone receptors in embryo implantation dysfunction mice endometrium / 中国中药杂志
China Journal of Chinese Materia Medica
;
(24): 373-376, 2005.
Artigo
em Chinês
| WPRIM
| ID: wpr-279159
ABSTRACT
<p><b>OBJECTIVE</b>To explore the mechanism of Jiantai liquid on the endometrium development of embryo implantation dysfunction mice.</p><p><b>METHOD</b>The model of embryo implantation dysfunction mice was induced by mifepristone and treated by Jiantai liquid. All animals were sacrificed on day 8 of pregnancy. Estradiol and progesterone concentrations in serum and endometrium tissue homogenates were measured by radioimmunoassay method, the endometial expressions of estrogen receptor (ER)and progesterone receptor (PR)assessed by immunohistochemical SP method.</p><p><b>RESULT</b>There were no significantly differences in the estradiol and progesterone concentrations in serum and uterus tissue homogenates among three groups( P > 0.05). Absorbency and area rate of ER, PR in model group' s gland and stroma were higher than those in model group(P < 0.05), which was similar with the control group( P > 0.05).</p><p><b>CONCLUSION</b>Jiantai liquid increase the implantation rate and improve the endometrial development by increasing the expressions of ER, PR in endometrium of embryo implantation dysfunction</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Implantação Tardia do Embrião
/
Farmacologia
/
Plantas Medicinais
/
Medicamentos de Ervas Chinesas
/
Receptores de Progesterona
/
Receptores de Estrogênio
/
Mifepristona
/
Química
/
Astragalus propinquus
/
Salvia miltiorrhiza
Limite:
Animais
Idioma:
Chinês
Revista:
China Journal of Chinese Materia Medica
Ano de publicação:
2005
Tipo de documento:
Artigo
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