Research progress on active ingredients of traditional Chinese medicines improved insulin resistance based on PPARs targets / 中国中药杂志
China Journal of Chinese Materia Medica
;
(24): 4355-4358, 2015.
Artigo
em Chinês
| WPRIM
| ID: wpr-279234
ABSTRACT
Peroxisome proliferator-activated receptors (PPARs) are nuclear transcriptional factors closely related to glucose and lipid metabolism, insulin sensitivity. Activation of PPARs targets treated type 2 diabetes, obesity, hypertension and other metabolic diseases by insulin resistance. Recently, a variety of active ingredients of traditional Chinese medicines (TCMs) have been proved to activate PPARs targets for improving insulin resistance, which has attracted widespread attention at home and abroad. In this paper, we reviewed the pathological mechanisms between insulin resistance and PPARs, and summarized the active ingredients of TCMs improved insulin resistance based on PPARs targets. This paper may provide some theoretical guidance for the development of new drugs and TCMs.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Farmacologia
/
Resistência à Insulina
/
Medicamentos de Ervas Chinesas
/
Receptores Ativados por Proliferador de Peroxissomo
/
Tratamento Farmacológico
/
Genética
/
Doenças Metabólicas
/
Metabolismo
Limite:
Animais
/
Humanos
Idioma:
Chinês
Revista:
China Journal of Chinese Materia Medica
Ano de publicação:
2015
Tipo de documento:
Artigo
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