Changes in the inferior alveolar vessels and angiogenesis following mandibular lengthening with different rates of distraction / 华西口腔医学杂志
West China Journal of Stomatology
;
(6): 203-224, 2002.
Artigo
em Chinês
| WPRIM
| ID: wpr-279630
ABSTRACT
<p><b>OBJECTIVE</b>The purpose of this study was to study the changes in the inferior alveolar vessels and angiogenesis following mandibular lengthening with different rates of distraction.</p><p><b>METHODS</b>Bilateral mandibular corticotomies were performed in 6 goats. The mandibles in 6 goats were lengthened 10.0 mm using a custom-made distractor with different rates of distraction (1.0 mm/d[n = 3] and 2.0 mm/d [n = 3]); the other 2 nondistracted mandibles served as control. The goats with distracted mandibles were killed at 2 weeks after completion of distraction. The inferior alveolar vessels with distracted calluses were harvested and processed for histologic and morphometric evaluation.</p><p><b>RESULTS</b>No pathological changes in the inferior alveolar vessels were found following mandibular osteodistraction. However, the number of microvessels within distraction gap in the animals distracted at a rate of 1.0 mm/day was greater than that in the goats distracted using a rate of 2.0 mm/day, and more mature newly formed bone trabeculae was observed.</p><p><b>CONCLUSION</b>There were no significant changes in the inferior alveolar vessels after mandibular lengthening with distraction osteogenesis, but rapid distraction may have adverse effects on the aniogenesis in the distraction gap.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Osteotomia
/
Fisiologia
/
Cirurgia Geral
/
Vasos Sanguíneos
/
Capilares
/
Cabras
/
Neovascularização Fisiológica
/
Osteogênese por Distração
/
Processo Alveolar
/
Mandíbula
Limite:
Animais
Idioma:
Chinês
Revista:
West China Journal of Stomatology
Ano de publicação:
2002
Tipo de documento:
Artigo
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