Clinical features and prognostic factors in children with fulminant myocarditis / 中国当代儿科杂志
Chinese Journal of Contemporary Pediatrics
;
(12): 1232-1236, 2015.
Artigo
em Chinês
| WPRIM
| ID: wpr-279935
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the clinical features and prognostic factors in children with fulminant myocarditis.</p><p><b>METHODS</b>The clinical data of 24 children with fulminant myocarditis were retrospectively analyzed. According to the prognosis, these children were classified into two groups survival (n=12) and death (n=12). The risk factors influencing prognosis in children with fulminant myocarditis were identified by logistic regression analysis.</p><p><b>RESULTS</b>Among the 24 cases of fulminant myocarditis, gastrointestinal symptoms were found as initial symptoms in 14 cases, neurological symptoms in 12 cases, respiratory symptoms in 1 case, and cardiac symptoms in 2 cases. On admission, serum levels of creatine kinase MB, troponin I, and brain natriuretic peptide (BNP) were all increased. Besides, left ventricular ejection fraction (LVEF) decreased in 22 cases (92%), cardiothoracic ratio increased in 10 cases, third-degree atrioventricular block was observed in 8 cases, ST-segment changes were found in 11 cases and ventricular tachycardia was identified in 2 cases. LVEF in the death group was lower than in the survival group (P<0.05), while the peak level of serum BNP during hospitalization in the death group was higher than in the survival group (P<0.05). The multivariate logistic regression analysis revealed that LVEF was the risk factor influencing prognosis (OR=7.418; P<0.05).</p><p><b>CONCLUSIONS</b>Fulminant myocarditis has no specific clinical features in children. A decreased LVEF is a risk factor for poor prognosis in children with fulminant myocarditis.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Prognóstico
/
Sangue
/
Modelos Logísticos
/
Função Ventricular Esquerda
/
Peptídeo Natriurético Encefálico
/
Eletrocardiografia
/
Creatina Quinase Forma MB
/
Miocardite
Tipo de estudo:
Estudo prognóstico
/
Fatores de risco
Limite:
Adolescente
/
Criança
/
Feminino
/
Humanos
/
Lactente
/
Masculino
Idioma:
Chinês
Revista:
Chinese Journal of Contemporary Pediatrics
Ano de publicação:
2015
Tipo de documento:
Artigo
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