Genotype of Rotavirus Vaccine Strain LLR in China is G10P15 / 病毒学报
Chinese Journal of Virology
;
(6): 170-173, 2015.
Artigo
em Chinês
| WPRIM
| ID: wpr-280278
ABSTRACT
Rotavirus is the leading causal agent of severe acute gastroenteritis in children aged <5 years. A specific pharmacologic agent for the treatment of rotavirus-infected children is lacking. In China, only the Luo Tewei oral vaccine (Lanzhou Institute of Biological Products, Shanghai, China), which is produced from Lanzhou lamb rotavirus vaccine (LLR), is available. Studies have hypothesized that the genotype of LLR is G10P[12], To identify the genotype of LLR by reverse transcription-polymerase chain reaction, we showed that the VP7 and VP4 genotypes of LLR were G10 and P[15], respectively, based on sequencing, alignment and phylogenetic analyses. In conclusion, we identified the genotype of rotavirus strain LLR to be G10P[15].
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Filogenia
/
Infecções por Rotavirus
/
Proteínas Virais
/
Virologia
/
Dados de Sequência Molecular
/
Química
/
China
/
Classificação
/
Homologia de Sequência de Aminoácidos
/
Rotavirus
Limite:
Humanos
País/Região como assunto:
Ásia
Idioma:
Chinês
Revista:
Chinese Journal of Virology
Ano de publicação:
2015
Tipo de documento:
Artigo
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