Analysis of pancreatic leaking-related risk factors after pancreaticoduodenectomy / 中华外科杂志
Chinese Journal of Surgery
;
(12): 752-754, 2009.
Artigo
em Chinês
| WPRIM
| ID: wpr-280622
ABSTRACT
<p><b>OBJECTIVE</b>To analysis the risk factors of pancreatic fistula after pancreaticoduodenectomy (PD).</p><p><b>METHODS</b>A retrospective clinical study had been done in 97 patients who underwent PD between June 2001 and June 2006. The two groups were first compared by the univariate analysis;logistic regression was then used to determine the effect of multiple factors on pancreatic fistula. A P-value of less than 0.05 was considered to be statistically significant.</p><p><b>RESULTS</b>Of the 97 patients, 13 patients were identified as having pancreatic fistula. Factors significantly increasing the risk of pancreatic fistula by univariate analysis included preoperative serum total bilirubin (P = 0.038), operative time (P = 0.003) and whether or not Braun anastomosis (P = 0.034), and prophylactic use of somatostatin (P = 0.003) after operation. A multivariate logistic regression analysis revealed the factors most highly associated with pancreatic fistula to be preoperative serum total bilirubin (OR = 11.687, P = 0.021) and postoperative prophylactic use of somatostatin (OR = 0.056, P = 0.020).</p><p><b>CONCLUSIONS</b>Preoperative serum total bilirubin more than 170 mmol/L was a risk factor of pancreatic fistula after PD, and postoperative prophylactic use of somatostatin was a protect factor of pancreatic fistula after PD.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Complicações Pós-Operatórias
/
Bilirrubina
/
Sangue
/
Somatostatina
/
Estudos Retrospectivos
/
Fatores de Risco
/
Fístula Pancreática
/
Pancreaticoduodenectomia
/
Usos Terapêuticos
Tipo de estudo:
Estudo de etiologia
/
Estudo observacional
/
Estudo prognóstico
/
Fatores de risco
Limite:
Adulto
/
Idoso
/
Feminino
/
Humanos
/
Masculino
Idioma:
Chinês
Revista:
Chinese Journal of Surgery
Ano de publicação:
2009
Tipo de documento:
Artigo
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