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Biomechanical strength of bone cement impregnated with diphosphonate / 中华外科杂志
Chinese Journal of Surgery ; (12): 465-468, 2009.
Artigo em Chinês | WPRIM | ID: wpr-280631
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the biomechanical strength of diphosphonate impregnated bone cement (DIBC).</p><p><b>METHODS</b>DIBC specimens were manufactured and randomly assigned to the control groups and the DIBC groups. According to the corresponding ASTM/ISO standards, the static biomechanical strength and the fatigue limit were tested systematically. The particle size distribution of diphosphonate powder was analyzed with the laser light scattering method. The fatigue test results, given as number of cycles-to-failure, were analyzed using the linearized format of the two-parameter Weibull function.</p><p><b>RESULTS</b>With the drug load increased, there was a slight increase in static biomechanical strength and a moderate decrease in fatigue limit, both with statistical significance. When immersed in PBS before the tests, the DIBC specimens presented an overall significant decrease of static biomechanical strength and fatigue limit. The profile of drug particle sizes presented a normal distribution.</p><p><b>CONCLUSIONS</b>The adopted diphosphonate is a much homogeneous powder which contains particles with a low range of sizes. The impregnation of diphosphonate exerted no or less negative effect on the biomechanical strength of the acrylic bone cement, of which the static strength of DIBC is maintained high above the ASTM/ISO standards.</p>
Assuntos
Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Resistência à Tração / Fenômenos Biomecânicos / Cimentos Ósseos / Teste de Materiais / Força Compressiva / Difosfonatos / Elasticidade Idioma: Chinês Revista: Chinese Journal of Surgery Ano de publicação: 2009 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Resistência à Tração / Fenômenos Biomecânicos / Cimentos Ósseos / Teste de Materiais / Força Compressiva / Difosfonatos / Elasticidade Idioma: Chinês Revista: Chinese Journal of Surgery Ano de publicação: 2009 Tipo de documento: Artigo