Advances in the association analysis of complex diseases / 中国医学科学院学报
Acta Academiae Medicinae Sinicae
;
(6): 271-277, 2006.
Artigo
em Chinês
| WPRIM
| ID: wpr-281217
ABSTRACT
To identify the genetic factors influencing complex diseases is a challenging problem. With the development of several technologies, such as large-scale genome sequencing, gene chips and mass spectrometry, and the successful completion of the first phase of International HapMap Project, it is feasible to explore the associations between hundreds of polymorphisms in the human genome, even the whole genome, and complex diseases in populations with large number of samples. The present paper briefly describes the results of the International HapMap Project, the merging whole-genome association study, and some new methods applicable to data including multiple loci.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Haplótipos
/
Projeto Genoma Humano
/
Teorema de Bayes
/
Estatísticas não Paramétricas
/
Biologia Computacional
/
Predisposição Genética para Doença
/
Métodos
Tipo de estudo:
Estudo prognóstico
Limite:
Humanos
Idioma:
Chinês
Revista:
Acta Academiae Medicinae Sinicae
Ano de publicação:
2006
Tipo de documento:
Artigo
Similares
MEDLINE
...
LILACS
LIS