Phosphorylated modification of genistein and their interaction with lysozyme / 药学学报
Acta Pharmaceutica Sinica
;
(12): 396-400, 2007.
Artigo
em Chinês
| WPRIM
| ID: wpr-281886
ABSTRACT
A series of genistein's phosphates were synthesized through a simplified Atherton-Todd reaction and the structures of the phosphates were determined by electrospray ionization mass spectrometry (ESI-MS) and NMR. In case of monophosporyl derivatives, NMR spectra show that substitutions occur at the 7-position of genistein but not at its 4' and 5-position. Moreover, the non-covalent complexes of lysozyme with the four new genistein phosphates were detected by ESI-MS.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Fosforilação
/
Espectroscopia de Ressonância Magnética
/
Muramidase
/
Química
/
Genisteína
/
Espectrometria de Massas por Ionização por Electrospray
/
Mapeamento de Interação de Proteínas
/
Interações Medicamentosas
/
Metabolismo
/
Métodos
Idioma:
Chinês
Revista:
Acta Pharmaceutica Sinica
Ano de publicação:
2007
Tipo de documento:
Artigo
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