The impact of N, N-dimethylacetamide on the health of workers / 中华劳动卫生职业病杂志
Chinese Journal of Industrial Hygiene and Occupational Diseases
;
(12): 834-836, 2011.
Artigo
em Chinês
| WPRIM
| ID: wpr-282489
ABSTRACT
<p><b>OBJECTIVE</b>To explore the hepatic toxicity and the exposure biomarkers of N, N-Dimethylacetamide.</p><p><b>METHODS</b>One hundred forty five objects were chosen by stratified random sampling method. The investigation was performed using questionnaire and physical examination. The air concentrations of DMAC in the workshops were monitored. The urine samples were collected and analyzed after work everyday or at the weekend. The correlation between the air concentrations of DMAC in the workshops and the concentrations of urinary NMAC wee analyzed by regression.</p><p><b>RESULTS</b>The air concentration of DMAC in the spinning workshop was higher than others. The morbidity of abnormal hepatic function was 12.4%, 61.1% of workers with abnormal hepatic function appeared in one year after exposure to DMAC in the workshops ( r=0.44, P<0.01).</p><p><b>CONCLUSION</b>The abnormal heptic function was found in workers exposed to DMAC for short period. The concentration of urinary NMAC can serve as the exposure biomarker of DMAC.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Urina
/
Biomarcadores
/
Monitoramento Ambiental
/
Inquéritos e Questionários
/
Exposição Ocupacional
/
Local de Trabalho
/
Poluentes Ocupacionais do Ar
/
Toxicidade
/
Testes de Função Hepática
/
Acetamidas
Limite:
Adolescente
/
Adulto
/
Humanos
/
Masculino
Idioma:
Chinês
Revista:
Chinese Journal of Industrial Hygiene and Occupational Diseases
Ano de publicação:
2011
Tipo de documento:
Artigo
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