Role of the cut-off value of serum neuron-specific enolase in differentiating small cell lung cancer from non-small cell lung cancer / 南方医科大学学报
Journal of Southern Medical University
;
(12): 858-859, 2006.
Artigo
em Chinês
| WPRIM
| ID: wpr-282896
ABSTRACT
<p><b>OBJECTIVE</b>To determine the cut-off value of serum neuron-specific enolase (NSE) level for distinguishing small cell lung cancer (SCLC) and non-small cell lung cancer (NSCLC).</p><p><b>METHODS</b>Serum NSE levels were measured by enzyme-linked immunosorbent assay in 137 patients with NSCLC or SCLC, and the best cut-off value was analyzed using ROC curve.</p><p><b>RESULTS</b>The positivity rate of serum NSE was significantly higher in patients with SCLC than in those with NSCLC (P<0.01). The best cut-off value was 15.45 microg/L using ROC curve, which gave a sensitivity of 66.7% and specificity of 65.7%.</p><p><b>CONCLUSION</b>Serum NSE level may allow simple and cost-effective differentiation of SCLC and NSCLC.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Patologia
/
Fosfopiruvato Hidratase
/
Sangue
/
Biomarcadores Tumorais
/
Carcinoma de Células Pequenas
/
Carcinoma Pulmonar de Células não Pequenas
/
Diagnóstico Diferencial
/
Neoplasias Pulmonares
Tipo de estudo:
Estudo diagnóstico
/
Estudo prognóstico
Limite:
Feminino
/
Humanos
/
Masculino
Idioma:
Chinês
Revista:
Journal of Southern Medical University
Ano de publicação:
2006
Tipo de documento:
Artigo
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