Hair follicle cell mixture forms hair follicle-like structures after subcutaneous implantation in nude mice / 南方医科大学学报

ABSTRACT

<p><b>OBJECTIVE</b>To observe the hair follicle regeneration after subcutaneous implantation of hair follicle cell mixture in nude mice.</p><p><b>METHODS</b>The hair papilla cells, dermal sheath cells, outer root sheath and fibroblasts of human scalp were mixed with the hair follicle epithelial cells and implanted subcutaneously in nude mice to observe the regeneration of the hair follicle.</p><p><b>RESULTS AND CONCLUSION</b>Formation of intact hair follicle-like structures was observed in the skin sections of the recipient nude mice, suggesting the feasibility of this approach for hair follicle regeneration in vivo.</p>