Clinical analysis of gastrointestinal stromal tumor: a report of 29 patients / 中华胃肠外科杂志
Chinese Journal of Gastrointestinal Surgery
;
(12): 139-141, 2006.
Artigo
em Chinês
| WPRIM
| ID: wpr-283366
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the clinical manifestations, diagnosis and treatment of gastrointestinal stromal tumor (GIST).</p><p><b>METHODS</b>Clinicopathological data of 29 cases with GIST from 2003 to 2005 were retrospectively analyzed.</p><p><b>RESULTS</b>The most common clinical manifestations were abdominal pain, distention or discomfort in 16 cases (55.2%), abdominal mass in 9 (31.0%), melena and hematemesis in 5 cases (17.2%). The tumor was located in the stomach in 16 cases, the small intestine in 9, the colorectum in 2, the esophagus in one, and the duodenum in one case. All the cases underwent operation, included total gastrectomy in one case, subtotal gastrectomy in 8, partial gastrectomy in 4, local excision of the tumor in 5 cases, partial small intestine resection in 9 and right colectomy in 2 cases. The resection rate was 100% and no complication and death occurred. The positive rates of CD117(+) and CD34(+) were 93.1% and 51.7% respectively. After follow up from one to 2 years after operation, 2 cases died of tumor recurrence and metastasis, the others survived.</p><p><b>CONCLUSIONS</b>Immunohistochemical examinations of CD117 and CD34 are important diagnostic markers. Surgery is the main method of final diagnosis and treatment.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Patologia
/
Cirurgia Geral
/
Biomarcadores
/
Estudos Retrospectivos
/
Seguimentos
/
Proteínas Proto-Oncogênicas c-kit
/
Antígenos CD34
/
Tumores do Estroma Gastrointestinal
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Diagnóstico
/
Gastrectomia
Tipo de estudo:
Estudo diagnóstico
/
Estudo observacional
/
Estudo prognóstico
Limite:
Adulto
/
Idoso
/
Feminino
/
Humanos
/
Masculino
Idioma:
Chinês
Revista:
Chinese Journal of Gastrointestinal Surgery
Ano de publicação:
2006
Tipo de documento:
Artigo
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