Investigation of organophosphorous insecticides residue in Chinese crude drugs / 中国中药杂志

ABSTRACT

<p><b>OBJECTIVE</b>To study eleven organophosphorus insecticides residuals in four kinds of Chinese crude drugs.</p><p><b>METHOD</b>The organophosphorus insecticides were extracted with dichloromethane and cleaned-up with a mixture of Celite 545-activated carbon. The extracts were analyzed by gas chromatography equipped with a flame photometric detector (FPD).</p><p><b>RESULT</b>Analysis of fortified Chinese crude drug showed that the average recoveries ranged from 77.5% -112.3% at three different levels, the RSDs were below 10% (n = 4). Trace organophosphorous pesticide residues were found in samples of Rhizoma Atractylodis Macrocephalae and Flos Chrysanthemi.</p><p><b>CONCLUSION</b>A method was established for determination multi-residues in Rhizma Atractylodis Macrocephalae, Radix Curcumae, Bulbus Fritillariae Thunbergii and Flos Chrysanthemi. It provides a method for the risk assessment of organophosphorous pesticide in Chinese crude drugs.</p>