Effects of aqueous extract of Hedysarum austrosibiricum on metabolism of oxyen free radicals in subacute aging mice caused by D-galactose / 中国中药杂志
China Journal of Chinese Materia Medica
;
(24): 729-731, 2007.
Artigo
em Chinês
| WPRIM
| ID: wpr-283395
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the anti-aging effect of aqueous extract of Hedysarum austrosibiricum cultivated in Xin-jiang.</p><p><b>METHOD</b>Subacute aging model in mice was established by D-galactose (D-gal) and activities of SOD and GSH-PX, contents of MDA in brain and liver tissues, activities of MAO in brain tissue and immune indexes were determined.</p><p><b>RESULT</b>Aqueous extract of H. austrosibiricum Xinjiang markedly increased the activities of SOD and GSH-PX, significantly decreased contents of MDA in brain and liver tissues. MAO activities in brain tissue were also decreased. It also elevated the spleen and thymus indexes.</p><p><b>CONCLUSION</b>Aqueous extract of H. austrosibiricum might have anti-aging effect, which is implemented by eliminating oxyen free radicals, rising activities</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Farmacologia
/
Superóxido Dismutase
/
Encéfalo
/
Envelhecimento
/
Medicamentos de Ervas Chinesas
/
Extratos Vegetais
/
Distribuição Aleatória
/
Química
/
Sequestradores de Radicais Livres
/
Raízes de Plantas
Limite:
Animais
Idioma:
Chinês
Revista:
China Journal of Chinese Materia Medica
Ano de publicação:
2007
Tipo de documento:
Artigo
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