The clinical evaluation of Oratest in detecting oral mucosal lesions / 华西口腔医学杂志

ABSTRACT

<p><b>OBJECTIVE</b>The aim of the study was to evaluate the clinical efficacy of Oratest in detecting oral mucosal lesions.</p><p><b>METHODS</b>Sixty patients with oral mucosal lesions that were suspected as carcinoma or premalignant lesions were divided into two groups randomly. The lesions were stained with Oratest by topical application in one group and rinse application in another group. Staining results were recorded and compared with the pathological diagnosis.</p><p><b>RESULTS</b>The sensitivity of Oratest stain to oral carcinoma and dysplasia were 93.9% and 42.9%, respectively. The difference between rinse application and local application showed no significance(P > 0.01).</p><p><b>CONCLUSION</b>Oratest can be used as a method of diagnosing squamous cell carcinoma of oral mucosa, but its reliability in screening oral pre-malignant lesions is still uncertain.</p>