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An analysis of prognostic factors for malignant fibrous histiocytoma of bone / 中华外科杂志
Chinese Journal of Surgery ; (12): 733-736, 2011.
Artigo em Chinês | WPRIM | ID: wpr-285653
ABSTRACT
<p><b>OBJECTIVE</b>To study the risk factors related to the survival rate, recurrence and metastasis of malignant fibrous histiocytoma of bone.</p><p><b>METHODS</b>From July 1997 and July 2010, 56 patients with malignant fibrous histiocytoma of bone were treated. Univariate and multivariate analysis were performed to determine the probable risk factors including gender, age, tumor location, tumor size and so on.</p><p><b>RESULTS</b>Forty-four cases were followed up ranged from 2 weeks to 78 months (medium 33.3). The 5-year overall survival rate was 50.1%, local recurrence rate 40.9% with a median time of 12 months (3 to 60 months) and metastatic rate 27.5% (11/40) with a median time of 6.5 months (2 to 23 months). Univariate analysis indicated that gender, condition of presentation (primary case or recurrence case), tumor location, surgical margin and surgical stage were significantly related to survival rate (P < 0.05), and tumor location and surgical margin were related to local recurrence rate (P < 0.05), and important vessel or nerve invasion was related to metastatic rate (P < 0.05). Multivariate analysis showed that surgical margin and surgical stage were independent risk factors for survival rate, of which surgical margin was the independent risk factor for recurrence rate.</p><p><b>CONCLUSIONS</b>Surgical margin and surgical stage are independent risk factors for survival rate, of which surgical margin is the independent risk factor for recurrence rate.</p>
Assuntos
Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Patologia / Prognóstico / Neoplasias Ósseas / Análise Multivariada / Taxa de Sobrevida / Estudos Retrospectivos / Diagnóstico / Histiocitoma Fibroso Maligno / Recidiva Local de Neoplasia Tipo de estudo: Estudo diagnóstico / Estudo observacional / Estudo prognóstico / Fatores de risco Limite: Adolescente / Adulto / Idoso / Feminino / Humanos / Masculino Idioma: Chinês Revista: Chinese Journal of Surgery Ano de publicação: 2011 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Patologia / Prognóstico / Neoplasias Ósseas / Análise Multivariada / Taxa de Sobrevida / Estudos Retrospectivos / Diagnóstico / Histiocitoma Fibroso Maligno / Recidiva Local de Neoplasia Tipo de estudo: Estudo diagnóstico / Estudo observacional / Estudo prognóstico / Fatores de risco Limite: Adolescente / Adulto / Idoso / Feminino / Humanos / Masculino Idioma: Chinês Revista: Chinese Journal of Surgery Ano de publicação: 2011 Tipo de documento: Artigo