A multiple regression formula for the prediction of thyroid microcarcinoma / 中国医学科学院学报
Acta Academiae Medicinae Sinicae
; (6): 79-85, 2014.
Article
em Zh
| WPRIM
| ID: wpr-285921
Biblioteca responsável:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To establish a quantitative analysis formula for the prediction of thyroid microcarcinoma and decide the cut-off values for the recommendation of ultrasound-guided biopsy.</p><p><b>METHODS</b>The ultrasound characteristics of 830 subcentimeter thyroid nodules were retrospectively analyzed based on pathological results in this study. A diagnostic formula was developed using multivariate binary Logistic regression with the cut-off values for the recommendation of biopsy. The diagnostic values of each feature and the formula were evaluated.</p><p><b>RESULTS</b>The most suspicious ultrasound characteristics for subcentimeter thyroid nodules were solid echostructure (OR=41.97), microlobulated margin (OR=25.89), hypoechoic echogenicity(OR=10.36), no halo (OR=8.38), irregular margin (OR=4.26), taller than wide (OR=2.71), microcalcification (OR=1.92), and macrocalcification (OR=1.28). The sensitivity, specificity, and accuracy of the formula were 90.9%, 54.0%, and 72.5%, respectively.</p><p><b>CONCLUSION</b>This multiple regression formula is an objective tool for the evaluation of thyroid microcarcinoma, which can provide the cutoff values for the ultrasound guided biopsy.</p>
Texto completo:
1
Índice:
WPRIM
Assunto principal:
Patologia
/
Valores de Referência
/
Neoplasias da Glândula Tireoide
/
Diagnóstico por Imagem
/
Carcinoma
/
Modelos Logísticos
/
Análise Multivariada
/
Estudos Retrospectivos
/
Ultrassonografia
/
Nódulo da Glândula Tireoide
Tipo de estudo:
Diagnostic_studies
/
Guideline
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Adolescent
/
Adult
/
Aged
/
Aged80
/
Child
/
Female
/
Humans
/
Male
Idioma:
Zh
Revista:
Acta Academiae Medicinae Sinicae
Ano de publicação:
2014
Tipo de documento:
Article