The Role of Bile Carcinoembryonic Antigen in Diagnosing Bile Duct Cancer
Journal of Korean Medical Science
;
: 855-858, 2003.
Artigo
em Inglês
| WPRIM
| ID: wpr-28623
ABSTRACT
It is known that the fluids bathing tumors might contain a higher level of the carcinoembryonic antigen (CEA) than those found in the blood. Therefore, we evaluated the role of bile CEA in diagnosing bile duct cancer. One hundred and thirty two patients were prospectively studied. The patients were divided into 3 groups the bile duct cancer (n=32), pancreatic cancer (n=16), and benign biliary diseases (n=84) groups. Bile samples were obtained on the next day of the biliary drainage procedures. The mean bile CEA level in those with bile duct cancer (120.6+/-156.9 ng/mL) was significantly higher than those with pancreatic cancer and benign biliary diseases (32.0+/-28.5 ng/mL, 29.3+/-56.3 ng/mL). Using the level of 20 ng/mL, the sensitivity and specificity of bile CEA in the diagnosis of bile duct cancer from benign biliary diseases were 65.6% and 66.7%, respectively. Both the bile CEA and total bilirubin level were found to be an independent factor linked to bile duct cancer. This study result suggests that bile CEA level is a useful supplementary test for diagnosing bile duct cancer.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Bile
/
Neoplasias dos Ductos Biliares
/
Antígeno Carcinoembrionário
/
Valor Preditivo dos Testes
/
Estudos Retrospectivos
/
Sensibilidade e Especificidade
/
Estatística
Tipo de estudo:
Estudo diagnóstico
/
Estudo observacional
/
Estudo prognóstico
Limite:
Adulto
/
Idoso
/
Aged80
/
Feminino
/
Humanos
/
Masculino
Idioma:
Inglês
Revista:
Journal of Korean Medical Science
Ano de publicação:
2003
Tipo de documento:
Artigo
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