Antibiotic resistance of gram-negative Bacillis isolated from children with bronchopneumonia / 中国当代儿科杂志
Chinese Journal of Contemporary Pediatrics
;
(12): 20-22, 2011.
Artigo
em Chinês
| WPRIM
| ID: wpr-286916
ABSTRACT
<p><b>OBJECTIVE</b>To study the distribution and antibiotic resistance of gram-negative pathogens isolated from children with bronchopneumonia.</p><p><b>METHODS</b>The distribution and the results of susceptibility tests of 272 strains of gram-negative Bacillis isolated from children with bronchopneumonia during 2009 were analyzed.</p><p><b>RESULTS</b>Among the isolates, the common pathogens were Klebsiella pneumoniae and Escherichia coli. The extended-spectrum β-lactamase (ESBLs) production rate was 52.9%. Compared with the non-ESBLs producing strains, ESBLs-producing strains had a significantly higher drug resistance rate to many antibiotics except amikacin and meropenem (P<0.05). The lowest resistance to ESBLs producing gram negative strains was found for meropenem (0.7%), followed by imipenem, amikacin and cefoperazone/sulbactam.</p><p><b>CONCLUSIONS</b>More attentions should be paid to the high rate of drug-resistance of ESBLs producing strains in children. Antimicrobial therapy should be based on the results of drug resistance surveillance.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Broncopneumonia
/
Resistência Microbiana a Medicamentos
/
Tratamento Farmacológico
/
Bactérias Gram-Negativas
/
Microbiologia
Limite:
Criança
/
Criança, pré-escolar
/
Feminino
/
Humanos
/
Lactente
/
Masculino
/
Recém-Nascido
Idioma:
Chinês
Revista:
Chinese Journal of Contemporary Pediatrics
Ano de publicação:
2011
Tipo de documento:
Artigo
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