Prostaglandin E1 versus sildenafil in the management of erectile dysfunction / 中华男科学杂志
National Journal of Andrology
;
(12): 198-200, 2002.
Artigo
em Chinês
| WPRIM
| ID: wpr-287249
ABSTRACT
<p><b>OBJECTIVES</b>To evaluate the outcome of treatment in patients with erectile dysfunction (ED) using sildenafil or intracavernosal injection of prostaglandin E1(PGE1).</p><p><b>METHODS</b>54 patients with ED were randomly classified into two groups and received either oral sildenafil (group A) or intracavernosal injection of PGE1(group B) for 4-9 months with an average of 6 months.</p><p><b>RESULTS</b>The percentages of efficacy in the two groups were 80.0% and 83.3%, respectively. There was no statistical difference between group A and B (P > 0.05). Two of six patients who did not respond to sildenafal in group A achieved erections sufficient for sexual intercourse when the six patients received intracavernous injection of PGE1. None of the four patients who did not respond to intracavernous injection of PEG1 in group B achieved erection sufficient for sexual intercourse when they received oral sildenafil.</p><p><b>CONCLUSIONS</b>Both oral sildenafil and intracavernous injection of PGE1 are effective for patients with ED of various etiologies. The patients who do not respond to sildenafil can receive intracavernous injection therapy. The satisfactory results can probably achieved.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Piperazinas
/
Purinas
/
Sulfonas
/
Alprostadil
/
Vias de Administração de Medicamentos
/
Administração Oral
/
Resultado do Tratamento
/
Usos Terapêuticos
/
Tratamento Farmacológico
/
Citrato de Sildenafila
Limite:
Adulto
/
Idoso
/
Humanos
/
Masculino
Idioma:
Chinês
Revista:
National Journal of Andrology
Ano de publicação:
2002
Tipo de documento:
Artigo
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