Effects of Astragalus membranaceus and Panax notoginseng on the transformation of bone marrow stem cells and proliferation of EPC in vitro / 中国中药杂志
China Journal of Chinese Materia Medica
;
(24): 1761-1763, 2005.
Artigo
em Chinês
| WPRIM
| ID: wpr-287312
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the effect and the possible mechanism underlying the promotional effect of Astragalus membranaceus and Panax notoginseng on the transformation of bone narrow stem cells and proliferation of EPC.</p><p><b>METHOD</b>The marrow blood was collected in the patients with ischemia of lower limbs and BM-MNCs were separated and proliferated under different conditions. A. morphologic observation was performed and the ratio of CD34+ cells was measured.</p><p><b>RESULT</b>The shuttle shaped cells lined up as bunches with several round cells scattered. The ratio of CD34+ cells was significantly increased in groups treated with medium (P < 0.01) and lower (P < 0.05) dosages of A. membranaceus and medium (P < 0.01) and high dosages (P < 0.01) of P. notoginseng respectively as compared with control group.</p><p><b>CONCLUSION</b>A. membranaceus and P. notoginseng can promote the transformation and proliferation of EPC.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Farmacologia
/
Plantas Medicinais
/
Células-Tronco Hematopoéticas
/
Medicamentos de Ervas Chinesas
/
Química
/
Antígenos CD34
/
Astragalus propinquus
/
Biologia Celular
/
Ginsenosídeos
/
Células Endoteliais
Limite:
Humanos
Idioma:
Chinês
Revista:
China Journal of Chinese Materia Medica
Ano de publicação:
2005
Tipo de documento:
Artigo
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