The pharmacodynamic research on fuxiye, a Chinese herbal lotion for external wash / 中国中西医结合杂志

ABSTRACT

<p><b>OBJECTIVE</b>To observe antisepsis, anti-swelling, and therapeutic effects of Fuxiye (FXY), a Chinese medical lotion for external wash in treating vaginitis model rats.</p><p><b>METHODS</b>The cervicitis rat model was induced by agar plate diffusion, ear auricle swelling induced by dimethylbenzene, and chemical stimulus. The in vitro antibiotic actions of FXY were observed. Besides, its effects on the swelling and inflammation in model rats were also observed.</p><p><b>RESULTS</b>FXY at 25 mg/mL could completely inhibit the growth of Pseudomonas aeruginosa, Escherichia coli, pyogenic Streptococcus, and Streptococcus agalactiae. FXY at 50 mg/mL could completely inhibit the growth of Staphylococcus aureus and Candida albicans. It obviously restrained dimethylbenzene induced ear auricle swelling. It significantly alleviated cervicitis induced by chemical stiumli.</p><p><b>CONCLUSION</b>FXY showed better effects on antisepsis, anti-inflammation, and treating cervicitis.</p>