Clinical study on a randomized, double-blind control of Shenwu gelatin capsule in treatment of mild cognitive impairment / 中国中药杂志

ABSTRACT

<p><b>OBJECTIVE</b>To evaluate the effectiveness of Shenwu gelatin capsule (compound Chinese ginseng and fleeceflower root etc) in the treatment on senile mild cognitive impairment.</p><p><b>METHOD</b>166 patients meeting criteria for mild cognitive impairment were selected from patients in Dongzhimen Hospital and were randomly assigned into a treatment group (n = 83 cases), given 5 capsules of Shenwu gelatin capsule, and a positive control group (n = 83 cases) , given 2 capsules of aniracetam with 3 placebo capsules. All subjects took this medication 3 times a day for 3 months, double-blind and double-moulding control were used in this study. At a baseline and end (three months later), all subjects were assessed using a battery consisting of MMSE and clinical memory scale (CMS).</p><p><b>RESULT</b>Both Shenwu gelatin capsule and aniracetam can remarkably increase the score of memory quotient (MQ), P < 0. 01. They have the similarly effectiveness, there are no statistical difference between the two groups in effectiveness of increasing memory scores.</p><p><b>CONCLUSION</b>Shenwu gelatin capsule has certain effects on mild cognitive impairment.</p>