Network-based local and global consistency of cardiovascular genes / 中国中药杂志
China Journal of Chinese Materia Medica
;
(24): 130-133, 2012.
Artigo
em Chinês
| WPRIM
| ID: wpr-288686
ABSTRACT
Drug targets discovery is one of the most important elements in new drug development, and a variety of methods have been developed recently from this point of view. This paper proposed a network-based local and global consistency for cardiovascular genes identification. Results were evaluated through the widely used database HPRD and DrugBank. Results showed that our algorithm can give reasonable candidate targets set. The method in this paper could be an impressive solution for targets searching.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Ligação Proteica
/
Algoritmos
/
Preparações Farmacêuticas
/
Doenças Cardiovasculares
/
Proteínas
/
Sistemas de Liberação de Medicamentos
/
Mapeamento de Interação de Proteínas
/
Bases de Dados de Proteínas
/
Redes Reguladoras de Genes
/
Descoberta de Drogas
Limite:
Humanos
Idioma:
Chinês
Revista:
China Journal of Chinese Materia Medica
Ano de publicação:
2012
Tipo de documento:
Artigo
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