Comparative study on toxicity of Euphorbia before and after being prepared by vinegar / 中国中药杂志
China Journal of Chinese Materia Medica
;
(24): 796-799, 2012.
Artigo
em Chinês
| WPRIM
| ID: wpr-288704
ABSTRACT
<p><b>OBJECTIVE</b>To study and compare the changes of toxicity of Euphorbia pekinensis, E. kansui and E. ebracteolata before and after being prepared by vinegar.</p><p><b>METHOD</b>Small intestinal accentuation of mice and peritoneal macrophage NO release experiments were assessed to investigate the changes of toxicity of the three Chinese Medicines of Euphorbia before and after being prepared.</p><p><b>RESULT</b>E. pekinensis, E. kansui and E. ebracteolata and vinegar can obviously promot small intestinal accentuation and peritoneal macrophage NO release with the intensity of toxicity in the order of E. kansui > E. pekinensis > E. ebracteolata. After being prepared with vinegar, the toxicity of the three medicines decreased obviously compared to crude one.</p><p><b>CONCLUSION</b>E. pekinensis, E. kansui and E. ebracteolata can induce inflammation and accelerate enterokinesis. After being prepared with vinegar, the irritation on Euphorbia decreased obviously.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Farmacologia
/
Medicamentos de Ervas Chinesas
/
Química
/
Macrófagos Peritoneais
/
Testes de Toxicidade
/
Raízes de Plantas
/
Ácido Acético
/
Euphorbia
/
Toxicidade
/
Intestino Delgado
Tipo de estudo:
Estudo diagnóstico
Limite:
Animais
Idioma:
Chinês
Revista:
China Journal of Chinese Materia Medica
Ano de publicação:
2012
Tipo de documento:
Artigo
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