Clinical effect of minocycline as adjunctive therapy to scaling and root planning on treatment of chronic periodontitis / 华西口腔医学杂志
West China Journal of Stomatology
;
(6): 32-35, 2006.
Artigo
em Chinês
| WPRIM
| ID: wpr-289013
ABSTRACT
<p><b>OBJECTIVE</b>To evaluate the efficacy of minocycline as an adjunct to scaling and root planning (SRP) in treating chronic periodontitis.</p><p><b>METHODS</b>64 male smokers with moderate to advanced periodontitis were randomly divided into two groups SRP alone (SRP) and SRP plus minocycline (SRP+M). All clinical parameters including plaque index (Pll), gingival index (GI), bleeding on probing (BOP), probing depth (PD) and attachment gain were recorded at baseline, 3 and 6 months after treatment.</p><p><b>RESULTS</b>According to PlI, GI and BOP, there was no significant difference between the two groups at 3 and 6 months after periodontal therapy (1 > 0.05). However, PD reduction and attachment gain were significantly greater for SRP+M than that for SRP (P < 0.05). For SRP+M and SRP groups, PD reduction were 1.98 mm and 1.32 mm, and attachment gain were 1.87 mm and 1.14 mm respectively. Deep pockets in SRP+M group showed more obvious PD reduction (3.48 mm versus 2.21 mm, P < 0.01) and attachment gain (2.62 mm versus 1.23 zmm, P < 0.01) than that in SRP group.</p><p><b>CONCLUSION</b>Treatment with SRP plus locally delivered minocycline is more effective than SRP alone in male smokers with chronic periodontitis. Mechanical debridement plus locally delivered antibiotics are recommended especially for smokers with deep pocket periodontitis.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Bolsa Periodontal
/
Periodontite
/
Índice Periodontal
/
Índice de Placa Dentária
/
Seguimentos
/
Raspagem Dentária
/
Aplainamento Radicular
/
Perda da Inserção Periodontal
/
Periodontite Crônica
/
Minociclina
Tipo de estudo:
Estudo observacional
/
Estudo prognóstico
Limite:
Adulto
/
Humanos
/
Masculino
Idioma:
Chinês
Revista:
West China Journal of Stomatology
Ano de publicação:
2006
Tipo de documento:
Artigo
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