Antibacterial effect of nHA-PA66 in vitro / 华西口腔医学杂志

ABSTRACT

<p><b>OBJECTIVE</b>To evaluate the antibacterial activity of nHA-PA66 on the predominant bacteria of infected root canal in vitro.</p><p><b>METHODS</b>Agar diffusion method was the testing method. Porphyromonas gingivalis (P. gingivalis), Fusobacteria nucleatum (F. nucleatum) and Prevotalla intermedius (P. intermedius) were the tested bacteria. The powder and polymerized film of nHA-PA66 were the test mateials while the CCQ and filter paper as the control.</p><p><b>RESULTS</b>nHA-PA66's powder showed good antebacterial effect on the P. gingivalis and P. intermedius, its film was weaker. Both of them had no effect on F. nucleatum.</p><p><b>CONCLUSION</b>nHA-PA66's antibacterial effect was not ideal, for better clinical results, some additives can be included.</p>