Experimental study on allogeneic mandible transplantation combined with basic fibroblast growth factor / 浙江大学学报·医学版
Journal of Zhejiang University. Medical sciences
;
(6): 26-29, 2002.
Artigo
em Chinês
| WPRIM
| ID: wpr-289330
ABSTRACT
OBJECTIVE:
To study the effect of basic fibroblast growth factor(b-FGF) on revascularization and bone remodeling of allogeneic mandible transplantation in repair of mandible defects in rabbits.METHODS:
The mandible defects of 20 adult rabbits were created in both sides. The defects on the left side were implanted with allogeneic bone and local administration of b-FGF; the defects on the right side were only repaired with allogeneic bone as control group. At 1, 3 months after operation, the revascularization and bone remodeling were observed by ink-gelation vascular perfusion-transparency and histological examination.RESULTS:
The allogeneic bone and b-FGF group had more marked vascularization and more quick and complete bone formation than control group.CONCLUSION:
b-FGF can improve revascularization and bone formation after allogeneic mandible transplantation; allogeneic bone combined with b-FGF is a promising bone substitute in clinical uses.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Journal of Zhejiang University. Medical sciences
Ano de publicação:
2002
Tipo de documento:
Artigo
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