Serum levels of 25-hydroxyvitamin D in children with autism spectrum disorders / 中国当代儿科杂志
Chinese Journal of Contemporary Pediatrics
;
(12): 68-71, 2015.
Artigo
em Chinês
| WPRIM
| ID: wpr-289467
ABSTRACT
<p><b>OBJECTIVE</b>To examine serum 25-hydroxyvitamin D levels in children with autism spectrum disorders (ASD) and to explore the relationship between vitamin D level and ASD.</p><p><b>METHODS</b>Serum levels of 25-hydroxyvitamin D levels were determined by the HPLC-MS/MS method in 117 children with newly diagnosed ASD and 109 healthy controls. Vitamin D status were classified into normal (>30 ng/mL), insufficiency (10-30ng/mL) and deficiency (<10 ng/mL) according to 25-hydroxyvitamin D levels.</p><p><b>RESULTS</b>Serum level of 25-hydroxyvitamin D (19±9 ng/mL)in children with ASD was significantly lower than that in healthy controls (36±13 ng/mL; P<0.01). The rate of vitamin D insufficiency plus deficiency in the ASD group was significantly higher than in the control group (89.7% vs 52.3%; P<0.01).</p><p><b>CONCLUSIONS</b>Vitamin D insufficiency or deficiency is common in children with ASD and might be as one of the environmental or genetic factors for ASD.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Vitamina D
/
Deficiência de Vitamina D
/
Sangue
/
Transtornos Globais do Desenvolvimento Infantil
/
Epidemiologia
/
Cromatografia Líquida de Alta Pressão
Limite:
Criança
/
Criança, pré-escolar
/
Feminino
/
Humanos
/
Lactente
/
Masculino
Idioma:
Chinês
Revista:
Chinese Journal of Contemporary Pediatrics
Ano de publicação:
2015
Tipo de documento:
Artigo
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