Effects of etomidate infusion on serum cortisol in patients undergoing radical resection of lung cancer / 南方医科大学学报
Journal of Southern Medical University
;
(12): 1047-1049, 2010.
Artigo
em Chinês
| WPRIM
| ID: wpr-289996
ABSTRACT
<p><b>OBJECTIVE</b>To evaluate the effect of etodimate infusion on serum cortisol in patients undergoing radical resection of lung cancer operations during the perioperative period.</p><p><b>METHODS</b>Forty ASA I-II patients undergoing radical resection of lung cancer were randomly divided into etomidate group (Group E) and propofol group (Group P) (n=20). The serum cortisol was measured at 800 am (T(0)) before anesthesia, 400 pm (T(1)) on the day of operation and 24 h after the operation (T(2)) by radioimmunoassay.</p><p><b>RESULTS</b>Compared with that at T0, the serum level of cortisol significantly increased at 24 h after the operation in both groups (P<0.01); serum cortisol decreased lightly at T1, which was not statistically significant (P>0.05), and remained higher than the normal level. At each of the time points, serum cortisol levels were comparable between the two groups (P>0.05).</p><p><b>CONCLUSION</b>Etomidate infusion can not inhibit the synthesis of cortisol in patients undergoing radical resection of lung cancer.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Pneumonectomia
/
Período Pós-Operatório
/
Cirurgia Geral
/
Sangue
/
Hidrocortisona
/
Etomidato
/
Anestesia Geral
/
Neoplasias Pulmonares
/
Métodos
Limite:
Adulto
/
Feminino
/
Humanos
/
Masculino
Idioma:
Chinês
Revista:
Journal of Southern Medical University
Ano de publicação:
2010
Tipo de documento:
Artigo
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