A survival analysis of 1761 nasopharyngeal carcinoma cases diagnosed during 1976-2005 in Sihui city in Guangdong province / 中华预防医学杂志

ABSTRACT

<p><b>OBJECTIVES</b>To analyze the survival rate of nasopharyngeal carcinoma (NPC) and to evaluate the effect of intervention in this high risk population of NPC.</p><p><b>METHODS</b>Based on the cancer and vital registry systems, the follow-up data of 1761 NPC cases were collected. The measures of survival include 5-year, 10-year survival rate and median survival duration. Cox model was used to screen the independent prognosis factors.</p><p><b>RESULTS</b>The 5-year and 10-year survival rates of NPC cases in Sihui were 50.62% and 37.01%, and the median survival duration was 5.05 years. The survival rate of NPC cases diagnosed after 1993 was 58.8%, which was higher than that of cases diagnosed before 1993 (43.3%). Other prognosis factors included gender, age, clinical stage and diagnostic hospital.</p><p><b>CONCLUSION</b>There is a significant improvement of NPC survival in Sihui. That is mainly related to the improvement of NPC treatment. However, it needs to a long time observation to see a mortality reduction of NPC.</p>