The expression of the apoptosis-suppressive gene bcl-2 in the tissue of colon carcinoma / 华中科技大学学报(医学)(英德文版)
Journal of Huazhong University of Science and Technology (Medical Sciences)
; (6): 218-220, 2002.
Article
em En
| WPRIM
| ID: wpr-290554
Biblioteca responsável:
WPRO
ABSTRACT
The role of bcl-2 in the pathogenesis of colorectal tumor were studied. The expression of bcl-2 in the colorectal carcinoma and incisional edge tissue of tumor was detected by using SABC method. The results showed that the positive rate of bcl-2 was 69.6% in colorectal carcinoma and 47.6% in the incisional edge tissue respectively, with the difference being very significant (P = 0.001). Bcl-2 positive rate was associated with Dukes' stage, but had nothing to do with histological classification. It was concluded that bcl-2 might play a significant role in the development of colorectal carcinoma.
Texto completo:
1
Índice:
WPRIM
Assunto principal:
Patologia
/
Neoplasias Retais
/
Adenocarcinoma
/
Apoptose
/
Neoplasias do Colo
/
Proteínas Proto-Oncogênicas c-bcl-2
/
Genética
/
Estadiamento de Neoplasias
Limite:
Adult
/
Female
/
Humans
/
Male
Idioma:
En
Revista:
Journal of Huazhong University of Science and Technology (Medical Sciences)
Ano de publicação:
2002
Tipo de documento:
Article