Clinicopathologic features and prognostic factors of gastric gastrointestinal stromal tumor with synchronous gastric cancer / 中华胃肠外科杂志
Chinese Journal of Gastrointestinal Surgery
;
(12): 247-250, 2012.
Artigo
em Chinês
| WPRIM
| ID: wpr-290810
ABSTRACT
<p><b>OBJECTIVE</b>To evaluated the clinicopathologic features and prognostic factors of gastric gastrointestinal stromal tumor(GIST) with synchronous gastric cancer.</p><p><b>METHODS</b>The clinicopathologic records of 122 patients with gastric GIST who underwent surgical treatment from April 2000 to June 2010 were analyzed retrospectively. Twenty-six patients presented synchronous gastric cancer(group A), while 96 patients did not(group B). The clinicopathologic features of gastric GIST were compared between the two groups. Potential prognostic factors were evaluated by univariate and multivariate analyses.</p><p><b>RESULTS</b>Gastric GIST in group A were associated with smaller tumor diameter (P<0.01), lower mitotic count(P<0.05), lower Fletcher classification(P<0.01), and lower rate of pre-operative diagnosis(23.1% vs. 97.9%, P<0.01). On univariate analysis, maximum tumor diameter (P<0.01), mitotic count (P<0.01), Fletcher classification (P<0.01) and synchronous gastric cancer(P<0.05) were the predictive factors of survival. Multivariate analysis showed that Fletcher classification(P<0.05) and synchronous gastric cancer (P<0.01) were independent prognostic factors.</p><p><b>CONCLUSIONS</b>In patients with synchronous gastric GIST and gastric cancer, Fletcher classification of GIST is usually very low or low invasion risk and has minimal impact on the prognosis. Survival depends primarily on the gastric cancer.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Patologia
/
Prognóstico
/
Neoplasias Gástricas
/
Cirurgia Geral
/
Estudos Retrospectivos
/
Tumores do Estroma Gastrointestinal
Tipo de estudo:
Estudo observacional
/
Estudo prognóstico
Limite:
Feminino
/
Humanos
/
Masculino
Idioma:
Chinês
Revista:
Chinese Journal of Gastrointestinal Surgery
Ano de publicação:
2012
Tipo de documento:
Artigo
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