Long-term changes after transplantation of expanded skin in dogs / 中华整形外科杂志

ABSTRACT

<p><b>OBJECTIVE</b>To investigate the long-term changes of expanded skin after transplantation.</p><p><b>METHODS</b>The expanded skin in dogs at 0 week, 3 weeks, 6 weeks, 3 months and 6 months after transplantation was observed through areas, histomorphological, electron microscopic, collagen content, biomechanical, and immunohistochemical methods.</p><p><b>RESULTS</b>The expanded skin was close to the control groups in all observations.</p><p><b>CONCLUSION</b>The biological changes after expansion remain in 3 months. The expanded skin will gradually recover to normal in 3-6 months. It is similar to a wound repair process.</p>